Peptides are the biggest rage in anti-aging skin care, however due to their high cost, the effects of most peptide creams are minimal because they lack the proper amount of ingredients. Since our skin consists mostly of collagen, that which gives it suppleness and support, as we age we lose collagen and our skin becomes thin and wrinkled.
Collagen is a protein in the flesh and connective tissues. It is the main component of connective tissue, and is the most abundant protein, making up about 25% to 35% of the whole-body protein content. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendon, ligament and skin - the fibroblast is the most common cell which creates collagen. Fibroblast is a type of cell that synthesizes the extracellular "matrix" and collagen.
The main function of fibroblasts is to maintain the structural integrity of connective tissues by continuously secreting precursors of the extracellular matrix. Fibroblasts secrete the precursors of all the components of the extracellular matrix, primarily the ground substance and a variety of fibers.
Argireline (Acetyl Hexapeptide-8) one of the most sought after anti-aging agents on the market and Matrixyl 3000 have shown to significantly decrease the visible appearance of wrinkles are a safer, less expensive and offers fabulous alternative to Botulinum Toxin (botox).
As we age, our skin gets thinner, drier and less resilient, collagen depletes by environmental elements and our beautiful, young, smooth skin slowly gets thinner and wrinkles appear. As a result, certain peptides in our produces. The National Institutes of Health (NIH) discovered that peptides send a "signal" to your skin letting it know collagen has been lost, thus it needs to produce more. However, when the aging cycle continues, the "signal" depletes, thus the much needed peptides no longer produce.
In their research they stated, "Wrinkling of the skin is the most obvious sign of deterioration of the human body with age. This process involves a number of genetic, constitutional, hormonal, nutritional, and environmental factors, in addition to the influence of frequently repeated facial movements during laughing, smoking, etc. The physiological basis and mechanism of action of the active cosmetic ingredient acetyl hexapeptide-8 (Argireline). They prepared two formulations: an emulsion with an external aqueous phase for normal to dry skin, and a gel for oily skin. Laboratory analyses, rheology tests and in vitro release assays were used to evaluate the stability of these formulations for cosmetic treatment.
Matrixyl 3000 & Acetyl Hexapeptide-8 (Argireline) Peptides, when applied directly to the skin tricks the skin into thinking that it has lost collagen recently and needs to make more. The most effective signal peptides for cosmetic are Acetyl Hexapeptide-8 and Matrixyl 3000. These peptides work to mimic the broken down collagen, causing your skin to naturally react by producing more collagen. The hexapeptide Argireline actually paralyzes the muscles, preventing them from contracting. When facial muscles receive a certain neurotransmitter, they contract, forming lines and wrinkles. Argierline destabilizes this neurotransmitter telling muscles NOT to contract, effectively preventing the formation of lines and wrinkles! Argireline is marketed specifically as a topical alternative to Botulinum Toxin A.